The simplest answer is the best one: choose a perfume that appeals to you. Each person's sense of smell is unique. Not only do we smell things differently, we also have visceral reactions to scents based on the associations and memories they evoke. Wear what makes you feel comfortable and confident. So, trust your instincts, but also leave open the possibility of acquired taste. If you're not sure, give a scent a chance by sampling it on several different occasions.
Always try a fragrance on skin before buying it, so that you can see how it reacts with your own body chemistry, and allow at least 30 minutes for the scent to develop before making a final decision. Although some people swear by the idea of finding a single signature fragrance, there's a danger of falling into the fragrance equivalent of a blue-eyeshadow time warp, and it's so much more fun to have a rotating fragrance wardrobe from which to choose!